INTERCEPT™ Blood System for Platelets

The INTERCEPT Blood System for Platelets consists of the INTERCEPT Processing Set for Platelets and the INTERCEPT Illuminator INT100/INT200 medical devices and is intended for the ex vivo preparation and storage of whole blood-derived and apheresis platelets. The system is used to inactivate a broad spectrum of viruses, bacteria, and parasites as well as contaminating donor leukocytes in platelet components. The device uses amotosalen (a photoactive compound) and low energy ultraviolet (UVA) illumination to photochemically treat platelet components. Platelets suspended in plasma with or without additive solutions can be processed with this system. Platelets suspended in 100% plasma must be processed using only the Large Volume or Dual Storage processing sets. When using platelet additive solutions, either the Smal Volume, Large volume , or Dual Storage processing sets can be used and the plasma to platelet additive solution ratio in the suspension medium needs to be approximately 35%/65%. The INTERCEPT Blood System is the only US/FDA and EU/MDR approved pathogen inactivation system for platelets and plasma