HAPPYCROSS

Second generation viscosupplement indicated in the treatment of ankle, hip, shoulder and knee osteoarthritis. Unique combination of HA and mannitol. - High concentration for prolonged activity HAppyCross™ contains high concentration of hyaluronic acid (1.6%) i.e. 35.2 mg/syringe. Happycross® estimated Molecular Weight 25MDa. - Cross-linked Hyaluronic Acid HAppyCross™ is a cross-linked hyaluronic acid gel (IPN-Like technology). Cross-linking: Ensures a gel-like rheological behaviour, maximizing then the mechanical properties of hyaluronic acid. Increases the residence time of the gel in the joint cavity, preventing biodegradation from free radicals and enzymes. IPN-Like Technology: A unique and patented cross-linking process. Compared to the classic cross-linking technique, the IPN-Like technology, or InterPenetrated Cross-linked Networks, involves combining, inserting one into another, two monophasic hyaluronic acid networks previously purified and cross-linked which are mechanically independent. Interpenetration of Cross-linked Networks: Optimizes the density of the chemical bonds while minimizing the use of reticulating agent (BDDE) within the monophasic gel, ensuring a longer-lasting effect of the product. Preserves the partial independence of the inter-penetrated networks and guarantees the gel is supple and easy to inject into the joint. Mannitol HAppyCross™ also contains high concentration of mannitol (77mg/syringe). Long-lasting effect: Mannitol is an anti-oxidant which protects hyaluronic acid chains from free radicals and limits their degradation, increasing then their residence time in the joint cavity. Analgesic effect: Due to its free radical scavenging properties, mannitol also ensures local analgesic effect. Safe HAppyCross™ is highly purified and results from bacterial fermentation.